June 28, 2002: And Baby Makes Five

Well the "big" week is drawing to a close. The embryo transplant went well, but we won't know if it worked for another week. Teresa, my little sister, has been a real trooper and actually argued with the doctors to implant more than they wanted to in an effort to increase the odds of success. Because there were 2 eight-cell embryos, 1 seven-cell and one five-cell (all over 6 are considered very viable), they wanted to implant no more than the best three. She argued for more and they compromised on four (the same number I had when I got pregnant with Kinsey and 2 1/2 years later Jillian). Just before they implanted them, the one 5 cell turned into a 6.

The odds are still against pregnancy on the first try and against more than one baby should she get pregnant. The odds of a perfect HLA match for Kinsey are about 25 percent for any one sibling, about 25 percent for a zero match, and about 50 percent for a half match (what Jillian and I both are). So we wait and hope.

Our appointment with Kinsey's doctor on Tuesday was eventful in that we got some pretty shocking news: he feels she needs to remain here another 6 to 12 months. We told him we knew he had no crystal ball, but based on the information he did have and his best guess, we wanted to know how long he thought she'd need to stay. He said 6 to 12 months with the very best scenario being 6. We were expecting 2 to 4 perhaps. Not sure what we were expecting, but we'd always talked about this in terms of being here for the summer and so winter in Wisconsin never really factored into our thoughts.

The doctor told us that the CAT Scan results were perhaps a little better but technically the same. He said, because of that, he was afraid to do anything to her meds as long as she was tolerating them. Her kidneys have suffered some, but overall, he feels she is tolerating them very well and the side effects are less risky than removal of them. Her neutrophils continue to trend upward, remaining above 500 the last several days, but as he pointed out, "she is on a lot of support." She is taking two powerful drugs each day 12 hours apart to promote white cell growth. Taking her off either right now would probably result in a sharp drop of her white cells. Long term use of these drugs can contribute to cancer risk, but again he said he felt the risk of side effects was less than the need for the drug right now. As I explained to my dad tonight about brushing Kinsey's teeth: we can't use a real toothbrush for fear of a bleed. He said, "what do you use?" I told him the hospital provided a low platelet toothbrush that didn't really clean her teeth very well. I said, "She'll probably have rotten teeth but better that than bleeding gums right now."

Speaking of platelets, she got them today from her Grandma Nancy. Nancy, my stepmother, has been through Hell to give those platelets with almost daily trips to the Red Cross blood center in Louisville. She has changed her diet and gotten a complete physical. And after a few failed attempts (either for low iron or a torn vein) they seem to have gotten the routine down. They arrived in Milwaukee this morning JUST in time as Kinsey's platelet count dropped to 6,000 (normal is 150,000 to 400,000). Nancy is giving again tomorrow and Kinsey will no doubt need another transfusion by Monday at the latest. We are so appreciative of Nancy's efforts and the support she's gotten from my dad (who chases her around the house, I understand, with black strap molasses for the iron boost). And we appreciate her boss Kenny Carter as well, who has been very understanding and flexible to let her off work to donate or attempt to donate several times. He joins our growing list of strangers who are helping to save Kinsey's life. She talks about all these people, too. She knows from friends and coworkers of her family members to old friends of ours who've never seen her or not seen her since she was a baby to total strangers who read about her on the net or in the paper—she is daily getting love and support from many, many people in many, many places. Again, thank you to all of you who are among that network of angels who keep her afloat.

Her red cell count dropped low enough today that they considered a whole blood transfusion but agreed to wait until tomorrow since she has not been having headaches or showing other signs of serious oxygen deprivation.

The bottom line from the doctor in the way of an update: "She is progressing but slowly and with a lot of support." He is still hoping for a full response to the drug protocol but still realistically believes that may not happen. He says we have bought ourselves some time, a lot of time, and because there is currently NO good donor, he would tweak everything he can to avoid transplant. We talked about the possible sibling match and he is hopeful as we are that that could become a reality in time should she need it. He says, "She will declare herself in 1 to 2 years," meaning she will have responded or failed to do so. Failure to do so would result in a transplant for sure. Success or failure for the transplant would result in either a fairly normal lifetime with little risk for recurrence (he says that doesn't usually happen with children the way it seems to with adults) or eventual death due to rejection or a resulting infection. For now, however, we are no longer in imminent danger of a life threatening infection. It could happen, but is far more unlikely with those 500 plus neutrophils. Again, most patients who have not responded to this treatment in 3 months will not go on to respond. Yet the average full response time is 4 months. That doesn't quite make sense to me, but I argued that she was responding, right? Well, response is defined by a neutrophil count of more than 500, no longer being transfusion dependent (with a platelet count of at least 50,000 and a red hemoglobin of at least 8, I think.) She currently has one of those three and seems a long way from having either of the other two. Her three month mark is coming up in a few days: July 1, but we are hoping her response will pick up in speed in that fourth month with the red cells and finally platelets. IF it doesn't work by 6 months (Oct. 1), he would consider a second round of drug therapy with the rabbit serum (she's already had the horse serum) and more cyclosporine, which he expects her to be on for at least another year regardless.

As long as she can be managed without going into crisis, even though she's very transfusion dependent, he will keep trying to avoid transplant. When and if it becomes obvious that transplant is the only hope, we just hope she has something better than a half match. Remember, right now I'm the best she's got and a transplant from me offers about a 20 percent survival rate. The survival rate with a matched sibling is as high as 90 percent. Come on twins!!!

The GOOD NEWS from that conference was that even though he is not backing down on any medications at this time, he will allow me to get additional training and administer them at "home" so that she will begin going to clinic 3 times a week instead of seven (except for the additional days she may need transfusions). My training begins tomorrow morning and continues on Saturday. He also said we could consider taking her on short weekend trips as long as her platelets were high enough before departure and I packed in a cooler all medications, plus pumps, tubes, and other supplies. We are considering that for next weekend but know not to plan anything and count on it at this point.

While we have been reeling from the news of 6 to 12 months and all that the news means to us and our lives: my job, our house, where and how we will live here, etc., we have also been dealing with trying to get to the bottom of Jillian's mystery fevers every 4 to 8 weeks for the last 17 months. While the doctor we took her to was exploring 3 theories and referred us to a Rheumatologist (appointment on the 10th), Kinsey's doctor casually mentioned that it sounded like "cyclic neutropenia." I called Jillian's doctor here to discuss and he argued that it did not fit. He called Kinsey's doctor and called me right back to say, while he didn't think it was likely, Dr. Margolis was the expert and it did seem possible. The only way to obtain positive or negative diagnosis: twice weekly blood tests for eight weeks. We started today. And she was SO brave. I was so proud of her. Here is this little 30 pound, 3 year old, saying, "Maybe this time it will only hurt a little bit" and after breakfast, "Come on Mommy, let's go get my blood test over with." I told her, "You are my hero." She laughed and said, "I not a hero. You a hero Mommy." I said, "Do you even know what a hero is Beanie?" She said, "A hero wears a really big red thing on his back and it ties on his neck like this" and she motioned around her neck, throwing her hands back to indicate a cape. She went on to tell me that she didn't have a red one but a green one, but didn't have it with her today.

When it came down to the needle stick, she balked and said to the nurse, "Oh please don't put that needle in my arm," and she cried a little, but overall, she was a real trooper. She did keep telling me her arm was broken the rest of the day. Kinsey told her it was too bad she didn't have a broviac. Her reward: her own little CD player like Kinsey has. Hers had to be, of course, pink. And tonight, they were sitting on different beds with headphones on jamming to different tunes. Amazing to have these little girls who seem so much older than they are in some ways and yet still babies in others.

I have to tell you that yesterday, when I had the second conversation with Jillian's doctor and he called me back to say she did need to start the blood tests, I lost it a bit. I asked him about how serious cyclic neutropenia was (it is characterized, by the way, by regular drops in neutrophil counts to nearly zero). He said not to worry, we'd talk about that IF that was the diagnosis. I said, "You can't expect me to sit in ignorance for eight weeks wondering and then just be pleasantly or miserably surprised by what this thing is." He said, "Well that's like planning how to spend the money before you've won the lottery." I said, "NO it is NOT like that." He said, "Well until we find out what she has, just don't fret." I was crying by this point and between sobs I said, "I have one child who has a life threatening illness, a psychologist reminded me today that while she is better, there is still a very real possibility she will die from it, and now you are telling me my other child may be seriously ill but you can't say how serious it might be just yet. I'm sorry, you cannot tell me not to fret. However, I will deal with it just as I am dealing with Kinsey, so don't worry." He said he'd have Kinsey's doctor call me because the truth was he'd never made this diagnosis and didn't know a lot about it. Dr. Margolis didn't call, but at 1 a.m. I emailed him along with Kinsey's pediatrician in Albuquerque and her former pediatrician. I heard back from two of the three so far with some words of comfort. Dr. Margolis says it is a "relatively benign" disease and as Jillian appears healthy and has been mostly healthy (with the exception of these fevers) for her life and the last 18 months particularly, he was not terribly concerned but just felt this needed to be ruled out. He also reiterated that Aplastic Anemia is not genetic and that whatever Jillian has he believes has no connection to Kinsey. It would just be hard for me to buy that if what Jillian has deals with neutrophils. I cannot believe a word I'd never heard of, a word no one can even spell has taken on such extraordinary meaning in my life! So with Jillian, too, we wait.

Kinsey, who is becoming so wise through this experience, shifted back into her "Why? why? why?" mode last night.
"Mommy—why did God pick me to get Aplastic Anemia?"
I told her I really didn't think God worked like that, but she pressed on so I said, "I don't know. Maybe he knew you'd be strong enough to beat it."
She said, "Well then, why did the dragon (our incarnation of AA) pick me?" Good question. I said, "Maybe the dragon knew how frightened you are of medicines and doctors and hospitals and so he thought you'd be easy to beat."
"Well, he was WRONG," she said. "I'm beating him. Kailee and I are fighting the same dragon and we are going to win!" I reminded her how many, many people she and Kailee both had helping fight that dragon. She said, "Doctor Margolis is a lot smarter than the dragon, too." "He sure is," I told her. "And we were smart enough to bring you to him."
"But Mommy, it will never be the same, will it? No matter what, our lives will never be regular again, never the same." I said she was right but that they would perhaps be better because we have all learned to appreciate each other more and love better. She said, "But Mommy we ALWAYS appreciated and loved each other." She's right, but I told her that we would always have our priorities in the right order now. We'd never again worry about money so much or needing a better car or being upset because it was raining. I told her that I had learned that no matter WHERE we were or HOW we had to live, we would be okay as long as we were together and that ALL that mattered was having a happy, healthy, whole family. She said, "Like Ohana from Lilo and Stitch (the latest Disney movie). It means family," she said, "and no one gets left behind." "Yes, like that," I told her. "But are we whole?" she asked. "Yes, we are happy and whole and soon we will all be healthy, too." But we will never forget this lesson no matter how long that is true. And what I didn't say is we will never feel totally safe from losing any of those again, but that itself will always ensure we will appreciate these things while we do have them.

She asked me if she would still be my baby when she was 100. I told her she would indeed, but I would most certainly be dead. She said, "Do you think I will live to be 105?" "Perhaps," I told her, "but maybe only 100." Let's not get greedy.

The psychologist I met with yesterday told me Kinsey has talked to her about dying several times and she said Kinsey most certainly knows how close she came to it and that it is still a possibility. I started crying and asked, "Does she seem afraid of it?" She told me Kinsey was not, she didn't think, just curious. That she has a strong sense of what Heaven is like and seems comforted by that. I could only nod. Kinsey does not talk to us directly about that because she can see how upsetting it is to us, but as I have shared with you, she talks about it indirectly. She asked Audrey the other day if everyone had to be buried when they died. Audrey explained the alternatives. She seemed interested but removed. I don't think she thinks she (or we) will need to worry about that anytime soon. I don't think so either. But I did tell Audrey, "I couldn't figure out why Dr. Margolis was so upbeat telling us she will be here another 6 to 12 months, and then it hit me: he didn't think she'd be alive another 6 to 12 months a few weeks ago."

And so, we wrestle with the decisions we must make regarding our lives and the impact of this news of such a long stay here, but we are certain about two things:
1. We will stay and
2. The rest is easy, especially when compared to the decisions we thought we might be faced with during this time. No one is suggesting we talk to Hospice to help with these little details of LIFE.

Finally, I feel compelled to write that in re-reading my own writing, I fear I've painted an ideal picture of a family who has learned so much, been enlightened so much and been transformed that we love each other and are kind to each other and appreciate each other fully each moment of each day. We enjoy every moment of our lives together. While that it true in a sense, it's not like that exactly. Those of you who call know we have some moments every day when one or both children are screaming. Living in a little room instead of a 2200 sq. foot house takes its toll. 18 hours of daily medication administration takes its toll. Sleep deprivation, fear, and worry take their toll. Audrey and I argue sometimes about the smallest stuff. We struggle to make each day a good one and to get everything done that MUST be done and have a little time for the "fun stuff." We try to keep people informed and try to thank those who love and support us and show our appreciation. We DO appreciate the laughter more, the little things, but we are sometimes more impatient and irritable. Audrey said to the girls (very indirect) the other day, "Mommy never used to raise her voice or throw things." I had just thrown a toy of Jillian's across the room after she hit the computer with it. Audrey is right. Mommy never used to do such things. We both get incredibly angry at Kinsey when she fights about her medicines or throws a temper tantrum for seemingly no reason. In the last two days, I have dragged her down the stairs, butt bumping along the way (knowing she was probably getting bruised) and Audrey has accidentally bloodied her lip while trying to get her pills down her (an easy thing to do when pushing pills into the mouth of a child with few platelets).

I was telling my dear friend Jill today about this and she said, "I can hear it, even now, in the way you are talking to Jillian." I had been trying to rush back here to Kathy's House to get one of Kinsey's meds so it wouldn't be late (as she was waiting for her platelet transfusion); Jillian was falling asleep and whining about a toy I couldn't find (it was the very one I'd thrown across the room); I was trying to gather the needed supplies, deal with Jillian, and talk on the phone and I was already upset that the medication was late. I was tired. And I WAS talking to Jillian with a very impatient, irritated tone. Audrey called me a Nazi tonight. I am trying so hard to get this routine down so that we can accomplish all that we must to keep her out of the hospital and yet ensure there's enough quality of life left to make it worth it. I hated for her to take her nap today after she was unhooked because she was wasting "free" time. What ends up happening some days is, "Okay girls you've got 30 minutes to do whatever fun thing you want, now hurry and have fun. Now." Squeezing it all in is a challenge. Not worrying about the little stuff is hard. Not worrying about the big stuff is impossible. But our lives and routines have gotten so much better. The improvement in Kinsey's mental health alone is enough of a reason to keep her here and not have her go back to NM or even start over elsewhere. She is trusting people more. She enjoys hospital school and the control of knowing she goes to the same room at the clinic and sees the same nurse (almost always). She even draws her own blood and helps them with other things. That sense of control and knowing what to expect make a huge difference and so I try to create that security here, too, in this little room and bigger house that is, for the moment, home. A bed time, rules, structure in the chaos and uncertainty that is unavoidable. And I try to do more and better each day to be the best mom I can be. One day I forget Jillian's vitamin, the next I forget to brush Kinsey's teeth in the morning. I once even forgot to flush with dextrose before saline with the only drug not compatible with saline. It took three nurses to convince me I had not done irreparable harm.

We are looking at this stay differently now. And I keep thinking that it's no longer temporary enough to warrant certain exceptions to how things should be. I want to figure out how to make living here as normal as possible. And yet I cannot yet imagine how to do so. I told Audrey last night, "How in the hell did we get here to this place in our lives, with one sick child, maybe two, and possibly one (or more) on the way and we don't even know in 9 months where we will be, where or if I will be working at that time, how Kinsey will be. It's not like we're in a position to prepare the nursery. Could a baby live with us at Kathy's House?" She just shook her head, and then we remembered, "Details, details, details. We can deal with such details."


Previous Next
Top